Endocrinology & Diabetes

Latent Autoimmune Diabetes of Adults

It's an autoimmune form of diabetes that's comparable to T1D, but patients with LADA often have insulin resistance, which is similar to T2D, and they share several risk factors for the illness. According to studies, LADA patients develop antibodies against insulin-producing cells, and these cells quit releasing insulin at a slower rate than T1D patients. T1D and T2D appear to have genetic risk factors in common, although LADA is genetically separate from both. There is genetic and phenotypic heterogeneity within the LADA patient population, with variable degrees of insulin resistance and autoimmunity. LADA can thus be regarded as a hybrid type of T1D and T2D, with clinical and genotypic parallels to both, as well as variance within LADA in terms of autoimmunity and insulin resistance, based on current information.